Green-Lipped Mussel for Dog Joints: Benefits, Dosage & Side Effects

Green-Lipped Mussel for Dog Joints: Benefits, Dosage & Side Effects
Pros & Cons of Green Lipped Mussel for Dogs

Pros:

  • Packed with nutrients
  • Natural
  • Available in different forms
  • Dogs love the taste
  • Safe for all ages & breeds
  • Can be given alongside NSAID

Cons:

  • Not suitable for dogs with shellfish allergy
  • Can cause minor stomach discomfort initially

What is a Green-Lipped Mussel?

Did you know that one of the widely recognized natural joint supplements for dogs is sourced from the waters of New Zealand? Meet the green-lipped mussel (Perna canaliculus), a large shellfish distinguished by its vibrant green “lip” along the shell edge.

New Zealand Green Lipped Mussels on a table

Native to New Zealand, the green-lipped mussel can grow up to 24 centimeters in length. Its edible tissue is rich in bioactive compounds—such as omega-3 fatty acids, glycosaminoglycans, and other nutrients—that are extracted for use in supplements. The shell is typically discarded, while the beneficial components from the mussel’s meat are processed into formulations for humans and pets.

What makes the green-lipped mussel notable is its role in the traditional diet of some Māori communities, especially those living along the coast. Observational studies noted that these communities appeared to experience lower rates of joint discomfort than inland groups, prompting researchers to investigate the mussel’s potential anti-inflammatory properties. Since then, green-lipped mussel extracts have been studied for their possible benefits in managing joint stiffness and supporting mobility in both humans and dogs. While more research is needed to confirm the full extent of its effects, it remains a commonly used supplement for joint health worldwide.

Benefits of green-lipped mussels for dogs

Packed with nutrients for healthy joints

Green-lipped mussels (Perna canaliculus) are often praised for their rich nutritional profile, which may help support healthy joints in both dogs and humans. Their wide range of bioactive compounds includes healthy lipids—such as DHA (docosahexaenoic acid), EPA (eicosapentaenoic acid), furan fatty acids, phytosterols, sphingolipids, and diterpenes—as well as antioxidants like carotenoids and xanthophylls. These compounds are likely synthesized by marine algae, which serve as a primary food source for green-lipped mussels.

Multiple scientific publications and clinical trials have investigated the joint-health benefits of these active components. In their 2015 study, Perna canaliculus (Green-Lipped Mussel): Bioactive Components and Therapeutic Evaluation for Chronic Health Conditions, researchers Coulson, Palacios, and Vitetta highlight the diverse nutrients found in GlycOmega® green-lipped mussels, including:

  • Proteins
    • Amino Acids 
  • Complex Carbohydrates
  • Lipids 
    • Omega 3 Fatty Acids (EPA/DHA)
  • Glycosaminoglycans (GAGs)
  • Vitamins
    • Vitamin A, Vitamin D3, Vitamin E, Vitamin B12
  • Minerals
    • Copper, Zinc, Manganese, Boron, Chromium, Iron, Calcium, Phosphorus, Sodium, Potassium, Magnesium, Nickel, Selenium, Iodine, Sulphur

Natural joint care for dogs

Looking for a natural way to support your dog’s joints? Green-lipped mussel supplements provide a safe, effective alternative to synthetic joint medications—without artificial additives or harsh chemicals.

But not all green-lipped mussel products are created equal. They come in different forms, and how they’re processed can impact their effectiveness. Be sure to read the label carefully. Avoid products with fillers and other cheap ingredients. 

Different Forms of Green-Lipped Mussel Supplements

Powder – Versatile and easy to mix into food. Look for freeze-dried powder, which retains the highest nutrient levels.

Oil – Offers concentrated omega-3s, but some dogs may not like the taste.

Whole Dehydrated Mussels – A natural treat for dogs who enjoy chewing, though they may not provide a precise dosage.

Capsules & Soft Chews – Perfect for convenience and consistent dosing, ideal for picky eaters or dogs who need an easy-to-administer option.

💡 Pro Tip: If your dog is picky or you’re looking for a no-fuss supplement, capsules and soft chews are game-changers! Capsules offer a tasteless, odorless option that’s easy to hide in treats, while soft chews turn joint support into a delicious snack. Plus, both provide pre-measured, consistent dosing, so you never have to guess how much your pup is getting. Perfect for busy owners and dogs with sensitive stomachs! 

What to Look for in a Green-Lipped Mussel Supplement

To make sure your dog is getting the best joint support, look for supplements that check these boxes:

Freeze-Dried Processing – Preserves the highest amount of beneficial nutrients. Avoid air dried or flash dried is possible. 
High Concentration of Green-Lipped Mussel – No fillers, artificial preservatives, or unnecessary additives.
Convenient Format – Capsules or soft chews ensure consistent dosage, while powders allow easy mixing with food.

Every dog is different! Some love a sprinkle of powder on their food, while others prefer a soft chew or capsule. Try different formats to see what works best for your pup.

Green lipped mussel powder in a capsule for dogs

Dogs Love the Natural Taste! 🐶

If you’ve ever struggled to get your dog to take a supplement, here’s some good news— most dogs love the natural taste of green-lipped mussel! The mild, fishy flavour makes it easy to administer without the usual battle of hiding it in cheese or peanut butter. For many dogs, it’s more of a treat than a supplement!

Sustainably Sourced from New Zealand’s Pristine Waters 🌿

Many green lipped mussel products such as Flexipaw - green lipped mussel for dogs are made using sustainably farmed New Zealand green lipped mussels. This means you’re not only supporting your dog’s joint health but also contributing to responsible aquaculture that protects marine ecosystems.

Works Alongside NSAIDs for Extra Joint Support 💊

If your dog is already on NSAIDs (nonsteroidal anti-inflammatory drugs) for arthritis or joint pain, green-lipped mussel supplements can be used alongside these medications for additional support. They contain natural anti-inflammatory properties that may help enhance comfort and mobility. However, always consult your veterinarian before combining supplements with prescribed medications.

Backed by Science 🔬

Green-lipped mussels aren’t just another health trend— numerous studies have explored their joint-supporting benefits in both humans and animals, including dogs. While researchers are still investigating exactly how they work, studies suggest their unique mix of omega-3s, glycosaminoglycans (GAGs), and antioxidants may help to reduce inflammation and support joint function.

Safe for Dogs of All Ages & Breeds 🐾

From energetic puppies to senior dogs needing extra support, green-lipped mussel supplements are safe for all life stages. There’s no age restriction — as long as your pup is eating solid food, they can start benefiting from this natural joint support. Adding it early may help maintain healthy joints and mobility for years to come.

Green-Lipped Mussel Dosage for Dogs

How Much Green-Lipped Mussel Does Your Dog Need?

There’s no one-size-fits-all dosage when it comes to green-lipped mussel supplements. The right amount depends on several factors, including:
Your dog’s weight – Larger dogs need a higher dose than smaller breeds.
The supplement’s potency – Not all green-lipped mussel products are equally concentrated.
Your dog’s joint health – Dogs with existing mobility issues may benefit from a higher, vet-recommended dose.

For the best results, follow the dosage instructions on your product label and consult your vet if you're unsure.

Consistency is Key!

No matter the dosage, the most important thing is regularity. Green-lipped mussel works best when given daily, allowing the nutrients to build up in your dog’s system over time. Skipping doses may reduce its effectiveness, so making it part of your pup’s daily routine is essential.

Green-Lipped Mussel Capsules for Dogs
Green-Lipped Mussel Capsules for Dogs
Learn More


Below is the recommended dosage calculator and dosage chart for FlexiPaw Green-Lipped Mussel Capsules for Dogs:

FlexiPaw Dog Supplement Calculator

Weight of Dog

Green-lipped mussel powder per day

Flexipaw - green lipped mussel for dogs capsules per day

1 - 9 kg

500 mg

1 capsule

10 - 24 kg

1000 mg

2 capsules

25 - 39 kg

1500 mg

3 capsules

40+ kg

2000 mg

4 capsules

Side Effects of Green-Lipped Mussel for Dogs

For most dogs, green-lipped mussel supplements are safe and well-tolerated. There are no known serious side effects, but as with any supplement, it’s important to be aware of potential reactions.

Shellfish Allergies – A Rare but Important Concern

While uncommon, some dogs can have a shellfish allergy, just like humans. If your dog has a known shellfish allergy, do not give them green-lipped mussel supplements. If you’re unsure, introduce it gradually and monitor for any signs of an allergic reaction, such as:
🚨 Itchy skin or rashes
🚨 Vomiting or diarrhea
🚨 Swelling or breathing difficulties (seek immediate vet care!)

Mild Digestive Upset in Some Dogs

Some dogs may experience temporary stomach discomfort or gas when first starting green-lipped mussel supplements. This is normal and often subsides as their system adjusts. To minimize this, try:
Starting with a smaller dose and gradually increasing.
Giving the supplement with food to ease digestion.

Consult Your Vet if Your Dog Has Health Conditions

If your dog has existing medical conditions or is on prescription medication, always check with your veterinarian before adding any supplements to their routine.

Green Lipped Mussel for Dogs: The Bottom Line

Green-lipped mussel is a powerful, natural supplement that supports joint health and mobility in dogs. Sourced from the pristine waters of New Zealand, it’s packed with omega-3 fatty acids, glycosaminoglycans (GAGs), and antioxidants — key nutrients that help maintain strong, flexible joints at any age.

Because it’s safe for dogs of all ages and breeds, starting early can help proactively support joint health, keeping your dog active and comfortable for years to come.

When choosing a supplement, look for freeze-dried, high-concentration green-lipped mussel to ensure your pup gets the most potent joint-supporting benefits. And remember, consistency is key! Regular supplementation is what helps maintain long-term mobility.

Green-lipped mussel is generally well-tolerated with no known serious side effects and may even be used alongside NSAIDs for additional joint support. However, as with any supplement, always consult your veterinarian before starting your dog on a new health regimen.


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References

Coulson, S., Palacios, T., & Vitetta, L. (2015). Perna canaliculus (Green-Lipped Mussel): Bioactive components and therapeutic evaluation for chronic health conditions. Progress in Drug Research, 91–132. https://doi.org/10.1007/978-3-0348-0927-6_3 

Elliott, D., Servet, E., & Biourge, V. (2007). Nutritional management of canine osteoarthritis. Veterinary Focus, 17(3), 43–48.

Bui, L.M.; Bierer, T.L. Influence of green lipped mussels (Perna canaliculus) in alleviating signs of arthritis in dogs. Vet. Ther. 2003, 4, 397–407.

Bierer, T.L.; Bui, L.M. Improvement of arthritic signs in dogs fed green-lipped mussel (Perna canaliculus).J. Nutr. 2002, 132, 16345–16365.

Eason CT, Adams SL, Puddick J, Romanazzi D, Miller MR, King N, Johns S, Forbes-Blom E, Hessian PA, Stamp LK, Packer MA. Greenshell™ Mussels: A Review of Veterinary Trials and Future Research Directions. Veterinary Sciences. 2018; 5(2):36. https://doi.org/10.3390/vetsci5020036

Disclaimer: The content on this website is for educational purpose only. We recommend you talk to your veterinarian if you have any concerns, if the lameness worsens or are unsure. Products on this website are not intended to diagnose, cure, treat or prevent any disease. The statements made on this website have not been evaluated by the Food and Drug Administration.

 


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